{"product_id":"advantage-multi-topical-solution-for-cats-5-1-9-lbs-ferrets-orange-box","title":"Advantage Multi Topical Solution for Cats (Imidacloprid \u0026 Moxidectin) 5.1-9 lbs, Orange - US 7111","description":"\u003cp\u003e\u003cimg src=\"https:\/\/hardypaw.com\/cdn\/shop\/files\/rx-map.webp\" alt=\"Rx Map\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" data-files=\"rx-map.jpg\" loading=\"lazy\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\u003ch2\u003eMonthly Topical 5-in-1 Parasite Protection for Cats and Ferrets (5.1–9 lbs)\u003c\/h2\u003e\u003ch3\u003eProduct Description\u003c\/h3\u003e\u003cp\u003eAdvantage Multi Topical Solution (Orange) for Cats is an FDA-licensed, prescription-only once-monthly spot-on for cats and kittens 9 weeks or older weighing 5.1 to 9 lbs. It is also the only size approved for ferrets weighing at least 2 lbs. Each 0.4 mL single-dose tube combines imidacloprid (10%) and moxidectin (1%) for 5-in-1 broad-spectrum protection. One monthly application prevents heartworm disease, kills adult fleas, prevents flea infestations, treats ear mites, and clears roundworm and hookworm infections.\u003c\/p\u003e\u003ch3\u003eBenefits\u003c\/h3\u003e\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeartworm Disease Prevention:\u003c\/strong\u003e Moxidectin absorbs into the body after application, delivering continuous heartworm disease protection throughout the full monthly period.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKills Adult Fleas on Contact:\u003c\/strong\u003e Imidacloprid moves through the coat's natural lipid layer, taking down adult fleas on contact before they ever get the chance to bite.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevents and Treats Flea Infestations:\u003c\/strong\u003e Clears existing flea infestations and stops new ones from building up by killing fleas before egg-laying can occur.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats and Controls Ear Mites:\u003c\/strong\u003e Clears Otodectes cynotis ear mite infestations, removing the need for separate ear drops or additional treatments.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats and Controls Roundworms:\u003c\/strong\u003e Works against adult and immature adult Toxocara cati roundworms, one of the most common intestinal parasites found in cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats and Controls Hookworms:\u003c\/strong\u003e Tackles adult, immature adult, and fourth-stage larvae of Ancylostoma tubaeforme hookworm infections in cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnly Size Approved for Ferrets:\u003c\/strong\u003e The Orange Box is the sole Advantage Multi for Cats size cleared for use in ferrets weighing at least 2 lbs for heartworm prevention and flea control.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForgives a Late Dose:\u003c\/strong\u003e A dose missed by a few days can simply be applied right away and the regular monthly schedule resumed without restarting.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafe for Kittens from 9 Weeks:\u003c\/strong\u003e Approved for kittens as young as 9 weeks old that weigh at least 2 lbs.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eIngredients\u003c\/h3\u003e\u003ch4\u003eComposition Table\u003c\/h4\u003e\u003ctable style=\"width: 56.9925%; height: 46px;\"\u003e\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 30.4209%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 69.302%; height: 19.6023px;\"\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 30.4209%; height: 19.6023px;\"\u003eImidacloprid\u003c\/td\u003e\n\u003ctd style=\"width: 69.302%; height: 19.6023px;\"\u003e40 mg (10%) per 0.4 mL tube\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 30.4209%; height: 19.6023px;\"\u003eMoxidectin\u003c\/td\u003e\n\u003ctd style=\"width: 69.302%; height: 19.6023px;\"\u003e4 mg (1%) per 0.4 mL tube\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\u003ch3\u003eHow to Use\u003c\/h3\u003e\u003ch4\u003eDirections for Use\u003c\/h4\u003e\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e Advantage Multi for Cats is an FDA-licensed prescription product obtained through or on the order of a licensed veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonthly Topical Application:\u003c\/strong\u003e Apply the full contents of one tube to your cat's skin once every 30 days, year-round, for uninterrupted protection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimum Dose:\u003c\/strong\u003e Each monthly application delivers a minimum of 4.5 mg\/lb (10 mg\/kg) imidacloprid and 0.45 mg\/lb (1 mg\/kg) moxidectin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStep 1, Open the Tube:\u003c\/strong\u003e Take one applicator tube from the package, hold it upright, and remove the cap.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStep 2, Break the Seal:\u003c\/strong\u003e Flip the cap over and press the opposite end firmly onto the tube tip, then twist to break the seal and remove the cap fully.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStep 3, Apply at the Base of the Head:\u003c\/strong\u003e Part the fur at the base of the head on the back of the neck until skin shows, press the tube tip directly onto the skin, and squeeze out the full contents in one spot before lifting the tube away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCritical Application Location:\u003c\/strong\u003e The base of the head is the one spot cats cannot reach to lick; applying the product anywhere else raises the risk of ingestion during grooming.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDo Not Apply to Irritated Skin:\u003c\/strong\u003e Never put this product on skin that is broken, inflamed, or already irritated.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFerret Dosing:\u003c\/strong\u003e Only the 0.4 mL Orange Box should be used in ferrets; the Turquoise Box under-doses and the Purple Box risks a serious overdose in ferrets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Cats Over 18 lbs:\u003c\/strong\u003e Your veterinarian will advise on which tube sizes to combine to reach the correct total dose for cats over 18 lbs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMissed Dose:\u003c\/strong\u003e A forgotten dose can be given the moment you notice; just carry on with the monthly schedule from there and never apply two doses close together.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any medication for your pet.\u003c\/p\u003e\u003ch3\u003eAdditional Information\u003c\/h3\u003e\u003ch4\u003ePrecautions\u003c\/h4\u003e\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eSick or Debilitated Cats:\u003c\/strong\u003e Do not use on sick, underweight, or debilitated cats; excessive lethargy has been noted in older or compromised animals in this category.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNever Administer Orally:\u003c\/strong\u003e This product must never be swallowed; every cat studied that ingested a full dose developed hypersalivation, vomiting, and poor appetite for at least one day.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevent Licking for 30 Minutes:\u003c\/strong\u003e Stop your cat from licking the treated area for at least 30 minutes; separation for up to 24 hours may be needed in multi-pet homes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Children Away:\u003c\/strong\u003e Children should not touch the treated area for at least 30 minutes after the product has been applied.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNever Use Dog Formulation on Cats:\u003c\/strong\u003e The dog version contains 2.5% moxidectin, more than double the cat formulation; using it on cats at any weight can cause serious toxicity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimum Age and Weight:\u003c\/strong\u003e Not suitable for cats younger than 9 weeks or under 2 lbs; for ferrets, effectiveness has not been confirmed in animals over 4.4 lbs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeartworm-Positive Cats:\u003c\/strong\u003e Adverse shock-like reactions have been reported in some heartworm-positive cats; testing before starting is advisable at your veterinarian's discretion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMulti-Pet Households:\u003c\/strong\u003e Cats that groom recently treated dogs can ingest enough of the higher-concentration dog product to develop adverse neurological reactions; keep them apart after dosing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman Safety:\u003c\/strong\u003e This product has been known to irritate human skin and eyes; make sure to wash up well with soap and water each time you apply it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDo Not Apply to Irritated Skin:\u003c\/strong\u003e Never apply to broken, inflamed, or already irritated skin.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpected Cosmetic Effects:\u003c\/strong\u003e Stiff hair, a damp appearance, or a light powdery residue at the treated spot are normal cosmetic effects and do not need veterinary attention.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplication Site Reactions:\u003c\/strong\u003e Persistent inflammation, significant itching, hair loss, skin redness, or progressive scabbing at the treated area should be assessed by a veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersalivation:\u003c\/strong\u003e Excessive drooling is the most commonly reported post-approval reaction and usually results from licking the treated area rather than true toxicity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDigestive Upset:\u003c\/strong\u003e Vomiting, reduced appetite, and diarrhea have been reported in some cats after treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy and Depression:\u003c\/strong\u003e Reduced energy and low mood have been reported and may be more noticeable in older or underweight cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBehavioral Changes:\u003c\/strong\u003e Hyperactivity, hiding, excessive grooming, agitation, and behavioral changes have been noted in some cats after treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurological Reactions:\u003c\/strong\u003e Trembling, loss of coordination, and tremors have been reported and may point to moxidectin-related effects that need immediate veterinary attention.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDeath (Rare):\u003c\/strong\u003e In rare cases death has been reported following use; a direct link to the product could not always be confirmed.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eStorage Information\u003c\/h4\u003e\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eTemperature Range:\u003c\/strong\u003e Room temperature storage works fine; just make sure the product does not go below 4°C (39°F) or above 25°C (77°F).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Away from Children and Pets:\u003c\/strong\u003e Store this prescription product somewhere children and other animals simply cannot reach to prevent accidental exposure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDo Not Use Past Expiration Date:\u003c\/strong\u003e The expiry date is printed on the bottom edge of the package; never use the product after this date has passed.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\u003ch3\u003eQ1: What parasites does Advantage Multi (Orange) protect cats and ferrets against?\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Advantage Multi Orange delivers 5-in-1 protection for cats, covering adult fleas, flea infestations, heartworm disease, ear mites, roundworms, and hookworms. For ferrets, it covers heartworm prevention and flea control. It does not protect against ticks or whipworms in either species.\u003c\/p\u003e\u003ch3\u003eQ2: How does Advantage Multi for Cats differ from Advantage Multi for Dogs?\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Both contain imidacloprid and moxidectin but are not interchangeable. The cat formulation contains 1% moxidectin while the dog version contains 2.5%, more than double the concentration. Applying the dog product to a cat, even at a similar weight, can cause serious moxidectin toxicity. Always use the product labeled specifically for cats.\u003c\/p\u003e\u003ch3\u003eQ3: Can the Orange Box be used in ferrets and are there any restrictions?\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes, the Orange Box is the only Advantage Multi for Cats size approved for ferrets weighing at least 2 lbs. The Turquoise Box under-doses ferrets and the Purple Box risks overdose. Effectiveness in ferrets over 4.4 lbs has not been confirmed. Always check with your veterinarian before treating a ferret.\u003c\/p\u003e\u003ch3\u003eQ4: My cat groomed itself after application and is now salivating heavily. What should I do?\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Drooling after licking the treated area is the most commonly reported reaction and is usually caused by the bitter taste of imidacloprid. Every cat studied that ingested a full dose experienced hypersalivation, vomiting, and reduced appetite for at least one day. Contact your vet promptly if symptoms are severe or if tremors or incoordination appear.\u003c\/p\u003e\u003ch3\u003eQ5: Is Advantage Multi (Orange) safe to use if my cat already has heartworms?\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Cats over 6 months may be tested for existing heartworm infection before starting treatment at the veterinarian's discretion. While no adverse reactions were seen in a controlled study of heartworm-infected cats treated at the label dose, a general risk of shock-like reactions exists in infected animals starting prevention products. Your vet should assess individual risk before beginning treatment.\u003c\/p\u003e\u003ch2\u003eClinical Research\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Imidacloprid\" title=\"Imidacloprid | c9h10cln5o2 | cid 86287518 - pubchem\" aria-label=\"Visit a webpage about Imidacloprid | c9h10cln5o2 | cid 86287518 - pubchem\"\u003eImidacloprid – PubChem (NIH)\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Moxidectin\" title=\"Moxidectin | c37h53no8 | cid 9832912 - pubchem\" aria-label=\"Visit a webpage about Moxidectin | c37h53no8 | cid 9832912 - pubchem\"\u003eMoxidectin – PubChem (NIH)\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.heartwormsociety.org\/heartworms-in-cats\" title=\"Heartworm in cats - american heartworm society\" aria-label=\"Visit a webpage about Heartworm in cats - american heartworm society\"\u003eAmerican Heartworm Society – Heartworm in Cats\u003c\/a\u003e\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"1 month","offer_id":64269826621809,"sku":"90209683-1-US7111","price":5.46,"currency_code":"JMD","in_stock":true},{"title":"6 months","offer_id":64269826654577,"sku":"90209683-US7111","price":32.75,"currency_code":"JMD","in_stock":true},{"title":"12 months","offer_id":64269826687345,"sku":"90209683-PK2-US7111","price":65.5,"currency_code":"JMD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1026\/6997\/5921\/files\/advantage-multi-topical-solution-for-cats-imidacloprid-moxidectin-822.jpg?v=1784968565","url":"https:\/\/catitoutlet.com\/products\/advantage-multi-topical-solution-for-cats-5-1-9-lbs-ferrets-orange-box","provider":"Catit outlet shop","version":"1.0","type":"link"}